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2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine
25I-NBOMe is a substance from the class of phenethylamines. Further information will follow after enrichment.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
Designations
IUPAC: 25I-NBOMe
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Effects & Pharmacology — Translation in progress
This section is being translated. Content is available in German.
View in German →Total duration 6-10 hours
Peak
2-4 hours
Onset
30-90 minutes
Total duration
6-10 hours
After effects
1-3 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Some combinations can be dangerous. Research before combining substances.
Lebensbedrohlich: NBOMe-Vasokonstriktion + stimulanzieninduzierte Hypertonie
25I-NBOMe ist ein hochpotenter 5-HT2A-Agonist mit klinisch relevanter 5-HT2B-Agonismus, die starke periphere Vasokonstriktion verursacht. Stimulanzien (Amphetamin, Kokain) erhöhen Katecholamine und verursachen zusätzliche Vasokonstriktion. Die Kombination erzeugt synergistische Vasokonstriktion mit Risiko für koronare Ischämie, Rhabdomyolyse durch periphere Minderperfusion, zerebrovaskuläre Ereignisse und Hyperthermie. 25I-NBOMe ist mit zahlreichen Todesfällen assoziiert, häufig durch kardiovaskuläre Komplikationen. Die steile Dosis-Wirkungs-Kurve macht die Substanz auch ohne Stimulanzien-Kombination hochriskant.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.