[2-(3-fluorophenyl)-1-methyl-ethyl]amine
1-(3-fluorophenyl)propan-2-amine (3-FA) is a substituted amphetamine with stimulant effects mediated by the release and reuptake inhibition of monoamines. The substance primarily acts on dopamine, norepinephrine, and serotonin transporters, resulting in increased activity in the central nervous system. Due to its structural similarity to other fluorinated amphetamines, 3-FA may potentially exhibit neurotoxic effects, and the limited research necessitates caution in assessing its risk profile.
Class
Not clearly classified yet
Pharmacological context
Mechanism
3-FA acts primarily as a releasing agent and reuptake inhibitor for...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: [2-(3-fluorophenyl)-1-methyl-ethyl]amine
Receptor Profile
Der 5-HT2A-Rezeptor ist ein Serotonin-Rezeptor der Klasse Gq-gekoppelter GPCRs. Er ist der primäre molekulare Angriffspunkt klassischer Psychedelika und spielt eine Rolle bei Kognition und Wahrnehmung.
Der Serotonintransporter (SERT/5-HTT) ist ein Natrium-abhängiger Monoamintransporter, der Serotonin aus dem synaptischen Spalt zurück in die präsynaptische Zelle transportiert. Er ist das primäre Ziel von SSRI und MDMA.
Der Dopamintransporter (DAT) ist ein Natrium-abhängiger Monoamintransporter, der Dopamin aus dem synaptischen Spalt entfernt. Er ist ein zentrales Ziel von Stimulants und spielt eine Schlüsselrolle im Belohnungssystem.
Substance Fingerprint
Pharmacological profile based on receptor binding, mechanism of action, and substance class. Limited data — interpret profile with caution.
Synapedia Evidence
Effects & Pharmacology is partially translated. Some details are still being expanded.
3-FA acts primarily as a releasing agent and reuptake inhibitor for monoamines, particularly affecting dopamine, norepinephrine, and serotonin transporters.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Risks & Harm Reduction translation in progress
English prose is being expanded. Safety-critical structured data may still be shown when available.
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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