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[2-(benzofuran-6-yl)-1-methyl-ethyl]amine
6-APB is a substance from the class of benzofurans. Further information will follow after enrichment.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
Designations
IUPAC: [2-(benzofuran-6-yl)-1-methyl-ethyl]amine
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Effects & Pharmacology — Translation in progress
This section is being translated. Content is available in German.
View in German →Total duration 6-8 hours
Peak
2-3 hours
Onset
30-60 minutes
Total duration
6-8 hours
After effects
2-4 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Neurotoxicity
possible
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Some combinations can be dangerous. Research before combining substances.
Lebensbedrohlich: Monoaminfreisetzer + MAO-Hemmung
6-APB setzt Monoamine frei und ist selbst Substrat der Monoaminoxidase. MAO-Inhibitoren blockieren den enzymatischen Abbau. Die Kombination kann zu einer massiven, unkontrollierten Akkumulation von Serotonin, Dopamin und Noradrenalin führen. Lebensbedrohliche Komplikationen: Serotoninsyndrom, hypertensive Krise, maligne Hyperthermie.
Serotoninsyndrom: Benzofuran-Empathogen + SSRI
6-APB (Benzofury) ist ein Benzofuran-Derivat mit MDMA-ähnlicher Pharmakologie: es setzt Serotonin, Dopamin und Noradrenalin frei. Die Wirkdauer ist deutlich länger als bei MDMA (6–10 h). SSRI blockieren die Serotonin-Wiederaufnahme am gleichen Transporter. Die Kombination erhöht die synaptische Serotoninkonzentration unkontrolliert und birgt ein relevantes Serotoninsyndrom-Risiko. Die verlängerte Wirkdauer von 6-APB verlängert auch das Zeitfenster der Gefährdung.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.