Laden…
Synapedia is an independent knowledge project about psychoactive substances and harm reduction. If the platform helps you learn something new, you can support its development.
Every bit helps keep the project alive.
N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
Agomelatine is a substance from the class of naphthalenes. Further information will follow after enrichment.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
Designations
IUPAC: N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Receptor Profile
Der Dopamintransporter (DAT) ist ein Natrium-abhängiger Monoamintransporter, der Dopamin aus dem synaptischen Spalt entfernt. Er ist ein zentrales Ziel von Stimulanzien und spielt eine Schlüsselrolle im Belohnungssystem.
Der 5-HT2C-Rezeptor ist ein Gq/11-gekoppelter Serotoninrezeptor, der an der Regulation von Appetit, Stimmung und Angst beteiligt ist. Er wird von verschiedenen Psychedelika als sekundäres Ziel aktiviert und moduliert dopaminerge Signalwege.
Substance Fingerprint
Pharmacological profile based on receptor binding, mechanism of action, and substance class. Limited data — interpret profile with caution.
Effects & Pharmacology — Translation in progress
This section is being translated. Content is available in German.
View in German →Total duration 24 hours
Peak
1-2 hours
Onset
1-2 hours
Total duration
24 hours
After effects
Variable
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Summary
Mögliche Nebenwirkungen umfassen Schwindel, Müdigkeit und gastrointestinale Beschwerden.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
May interact with other antidepressants.
Interactions with alcohol possible.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.