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2-[[(2S)-1-(2-phenylacetyl)prolyl]amino]acetic acid ethyl ester
Noopept is a synthetic nootropic that is primarily investigated for its potentially neuroprotective and cognitive-enhancing properties. It modulates glutamatergic receptors and may increase the expression of neurotrophic factors, which can contribute to the improvement of memory and learning ability. The substance is being studied in research regarding its effects on neurodegenerative diseases, with safety during intended use being assessed as relatively high.
Class
Not clearly classified yet
Pharmacological context
Mechanism
Erhöhung neurotropher Faktoren, Glutamatmodulation
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Noopept acts through the following pharmacological mechanisms:
Designations
IUPAC: 2-[[(2S)-1-(2-phenylacetyl)prolyl]amino]acetic acid ethyl ester
Receptor Profile
Der NMDA-Rezeptor ist ein ionotroper Glutamatrezeptor, der eine zentrale Rolle bei synaptischer Plastizität, Lernen und Gedächtnisbildung spielt. Er benötigt sowohl Glutamat als auch Glycin als Co-Agonisten zur Aktivierung.
Der AMPA-Rezeptor ist ein ionotroper Glutamatrezeptor, der die schnelle exzitatorische synaptische Übertragung im ZNS vermittelt. Er arbeitet eng mit NMDA-Rezeptoren bei der synaptischen Plastizität zusammen.
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Reported range 10–30 mg
Total duration 4–6 hours
Oral
| Tier | Dosage |
|---|---|
| Light | 5–10 mg |
| Reported | 10–30 mg |
| Strong | 30–50 mg |
Oral
Onset
30–60 minutes
Peak
1–2 hours
Total duration
4–6 hours
After effects
2–4 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Langzeitwirkungen und Sicherheit sind nicht umfassend untersucht.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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