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1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine
Vortioxetine is a multimodal serotonin modulator used as an antidepressant. It acts by inhibiting serotonin reuptake and modulating various serotonin receptors, which can lead to improvements in mood and cognitive functions. The substance is primarily used for major depression and is characterized by a favorable side effect profile. However, interactions and side effects are possible, which is why medical supervision is recommended.
Class
Serotonin-Wiederaufnahmehemmer
Pharmacological context
Mechanism
Vortioxetine wirkt als Serotonin-Wiederaufnahmehemmer und moduliert...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: 1-[2-[(2,4-dimethylphenyl)thio]phenyl]piperazine
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Receptor Profile
Der 5-HT1A-Rezeptor ist ein Gi/Go-gekoppelter Serotoninrezeptor, der als Autorezeptor auf serotonergen Neuronen und als Heterorezeptor in verschiedenen Hirnregionen vorkommt. Er moduliert Angst, Stimmung und Kognition.
Der 5-HT7-Rezeptor ist ein Gs-gekoppelter Serotoninrezeptor, der an der Regulation von zirkadianer Rhythmik, Thermoregulation und Kognition beteiligt ist. Er wird als mögliches therapeutisches Ziel bei Depression und Schlafstörungen erforscht.
Substance Fingerprint
Pharmacological profile based on receptor binding, mechanism of action, and substance class. Limited data — interpret profile with caution.
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Reported range 10–20 mg
Total duration 24 hours
Oral
| Tier | Dosage |
|---|---|
| Light | 5 mg |
| Reported | 10–20 mg |
| Strong | 20–30 mg |
Oral
Onset
1–2 weeks
Peak
2–4 weeks
Total duration
24 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Mögliche Nebenwirkungen umfassen Übelkeit, Schwindel und sexuelle Dysfunktion.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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