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Datura is a plant genus that contains tropane alkaloid compounds such as atropine, scopolamine, and hyoscyamine. These act as antagonists at muscarinic and nicotinic acetylcholine receptors and can induce intense anticholinergic delirium with hallucinations. Due to the narrow therapeutic index and toxic effects, there is a high risk of severe side effects and poisoning. The substance is rarely used in medicine but is known for its toxic and psychoactive effects.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
Designations
IUPAC: Datura
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Effects & Pharmacology — Translation in progress
This section is being translated. Content is available in German.
View in German →Total duration 8-12 hours
Peak
2-4 hours
Onset
30-60 minutes
Total duration
8-12 hours
After effects
Variable, up to 24 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Summary
Hohe Risiken von Delirien, Halluzinationen und anderen schweren Nebenwirkungen.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Some combinations can be dangerous. Research before combining substances.
Anticholinerges Delir und Aspirationsrisiko
Datura-Alkaloide (Scopolamin, Atropin, Hyoscyamin) blockieren muskarinische Acetylcholinrezeptoren und können schwere anticholinerge Vergiftungssyndrome auslösen: Delir, Halluzinationen, Tachykardie, Hyperthermie, Mydriasis, Harnretention. Ethanol verstärkt die ZNS-Depression und Bewusstseinseintrübung. Die Kombination erhöht das Aspirationsrisiko und die Gefahr schwerer Selbstgefährdung durch delirante Zustände.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.