Laden…
4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylic acid ethyl ester
Loratadine is a substance from the class of piperidines. Further information will follow after enrichment.
Class
Depressiva
Pharmacological context
Mechanism
H1-Antagonist
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Loratadine acts through the following pharmacological mechanisms:
Designations
IUPAC: 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylic acid ethyl ester
Receptor Profile
Der H1-Rezeptor ist ein Gq/11-gekoppelter Histaminrezeptor, der an allergischen Reaktionen, Wachheit und Thermoregulation beteiligt ist. Antagonismus verursacht Sedierung und wird therapeutisch als Schlafhilfe und Antiallergikum genutzt.
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Reported range 10 mg
Total duration 24 hours
Oral
| Tier | Dosage |
|---|---|
| Light | 5 mg |
| Reported | 10 mg |
| Strong | 20 mg |
Oral
Onset
1–3 hours
Peak
8–12 hours
Total duration
24 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Loratadine gilt als sicher bei empfohlener Dosierung, jedoch können Nebenwirkungen auftreten.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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