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Evidence-based guidance for risk minimisation
Harm Reduction
The safest option is always abstinence. If substances are used regardless, evidence-based precautions can meaningfully reduce risk. The guidance below is informational — it does not make substance use safe.
dosing
Hohes Binge-Konsum-Potenzial — Cathinone/NDRI sind bekannt für zwanghaftes Nachdosieren. Harte Grenzen setzen
health
Kein Konsum bei Herzerkrankungen, Hypertonie oder psychiatrischen Erkrankungen (Psychose-Risiko)
combinations
Keine Kombination mit MAO-Hemmern — lebensbedrohliche hypertensive Krisen möglich
harm_reduction
Intravenöser/nasaler Konsum erhöht Suchtpotenzial und Infektionsrisiko erheblich
harm_reduction
Ausreichend Wasser trinken — Hyperthermie und Dehydrierung bei körperlicher Aktivität
harm_reduction
Schlaf erzwingen nach Sitzung — Schlafentzug verstärkt psychotische Symptome
The following substances carry an elevated risk of dangerous interactions with MDPV. This is not exhaustive.
See the full Interactions page for details.
Disclaimer: This information is provided for educational purposes only and does not constitute medical advice. It does not make substance use safe. If you have concerns about substance use, please consult a qualified healthcare professional or contact a local drug support service.