6-(dimethylamino)-4,4-diphenylhexan-3-one
Normethadon is a synthetic opioid from the methadone group that primarily acts as an analgesic. It predominantly binds to μ-opioid receptors and has a high potential for dependence. Due to its pharmacological properties, it is used medically in some countries, but it carries a significant risk of overdose and abuse.
Class
Diphenylmethan-Derivate
Pharmacological context
Mechanism
Normethadon wirkt hauptsächlich durch die Bindung an...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: 6-(dimethylamino)-4,4-diphenyl-hexan-3-one
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Reported range 10–30 mg
Total duration 6–8 hours
Oral
| Tier | Dosage |
|---|---|
| Light | 5–10 mg |
| Reported | 10–30 mg |
| Strong | 30–60 mg |
Sublingual
| Tier | Dosage |
|---|---|
| Light | 2–5 mg |
| Reported | 5–15 mg |
| Strong | 15–30 mg |
IV
| Tier | Dosage |
|---|---|
| Light | 1–5 mg |
| Reported | 5–15 mg |
| Strong | 15–30 mg |
Onset
30–60 minutes
Peak
1–2 hours
Total duration
6–8 hours
After effects
2–4 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Hohe Abhängigkeitspotential und Risiko für Überdosierung.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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