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methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
Salvinorin A is a potent, naturally occurring psychedelic that primarily acts as a Kappa-opioid receptor agonist. It differs from classical psychedelics due to its unique mechanism of action without direct effects on serotonin receptors. The substance is derived from the plant Salvia divinorum and can induce intense, short-lasting alterations in consciousness. Due to its strong effects and potential psychological burden, a moderate risk profile is assumed.
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View German version →Receptor Targets
Mechanism of Action
Designations
IUPAC: Salvinorin A
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Effects & Pharmacology is partially translated. Some content may appear in German.
Salvinorin A primarily acts as an agonist at the Kappa-opioid receptor, leading to its psychedelic effects. It influences perception and consciousness by modulating neuronal activity in specific brain regions.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Total duration 30-60 minutes
Peak
5-15 minutes
Onset
seconds to minutes
Total duration
30-60 minutes
After effects
1-2 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Evidence
limited
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Opioids
Benzodiazepines
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.