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Ashwagandha is a plant traditionally used as an adaptogen that contributes to stress reduction and improvement of cognitive functions. The effects are based, among other things, on the modulation of the HPA axis and antioxidant effects. Studies suggest an anxiolytic effect that is partially mediated by GABA and NMDA receptors. The substance is considered safe when used properly with a low risk of side effects.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
Designations
IUPAC: Ashwagandha
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Receptor Profile
Der GABA-A-Rezeptor ist ein ligandengesteuerter Chloridkanal und der wichtigste inhibitorische Rezeptor im zentralen Nervensystem. Er besitzt multiple allosterische Bindungsstellen für verschiedene Substanzklassen.
Effects & Pharmacology — Translation in progress
This section is being translated. Content is available in German.
View in German →Total duration 8-12 hours
Peak
2-4 hours
Onset
1-2 hours
Total duration
8-12 hours
After effects
Mild, may last up to 24 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Summary
Kann bei einigen Personen Nebenwirkungen wie Magenbeschwerden oder Schläfrigkeit verursachen.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Sedatives
Antidepressants
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.