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(2S)-2-amino-5-(ethylamino)-5-keto-valeric acid
L-Theanine is a naturally occurring amino acid primarily found in green tea. It promotes relaxation and reduces anxiety without sedative effects. The substance modulates glutamate receptors and increases GABA concentration in the brain, which may contribute to improved cognitive function and stress reduction. L-Theanine is often used to support mental relaxation and concentration.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
L-Theanine acts through the following pharmacological mechanisms:
Designations
IUPAC: (2S)-2-amino-5-(ethylamino)-5-keto-valeric acid
Receptor Profile
Der NMDA-Rezeptor ist ein ionotroper Glutamatrezeptor, der eine zentrale Rolle bei synaptischer Plastizität, Lernen und Gedächtnisbildung spielt. Er benötigt sowohl Glutamat als auch Glycin als Co-Agonisten zur Aktivierung.
Der GABA-A-Rezeptor ist ein ligandengesteuerter Chloridkanal und der wichtigste inhibitorische Rezeptor im zentralen Nervensystem. Er besitzt multiple allosterische Bindungsstellen für verschiedene Substanzklassen.
Effects & Pharmacology — Translation in progress
This section is being translated. Content is available in German.
View in German →Total duration 8-10 hours
Peak
1-2 hours
Onset
30-60 minutes
Total duration
8-10 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Summary
L-Theanin gilt als sicher und hat ein niedriges Risiko für Nebenwirkungen.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Based on substance class, receptors, mechanisms, and effect profile.