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Evidence-based guidance for risk minimisation
Harm Reduction
The safest option is always abstinence. If substances are used regardless, evidence-based precautions can meaningfully reduce risk. The guidance below is informational — it does not make substance use safe.
combinations
Tryptamin-Klasse: besonders gefährlich in Kombination mit MAO-Hemmern (inkl. Harmalin aus Ayahuasca)
dosing
AMT: extrem lange Wirkdauer (12–24h) — volle 2 Tage freie Zeit einplanen
dosing
Niedrig einsteigen — Tryptamine variieren stark in Potenz, genaue Dosierung kritisch
setting
Tripsitter bei Erstkonsum obligatorisch
dosing
Nüchtern konsumieren — Essen verlangsamt und verändert Resorption
combinations
Keine Kombination mit Lithium (Krampfrisiko)
The following substances carry an elevated risk of dangerous interactions with Diethyltryptamine. This is not exhaustive.
See the full Interactions page for details.
Disclaimer: This information is provided for educational purposes only and does not constitute medical advice. It does not make substance use safe. If you have concerns about substance use, please consult a qualified healthcare professional or contact a local drug support service.