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(4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Oxycodone is a semisynthetic opioid primarily used as a strong analgesic. It acts primarily as an agonist at the μ-opioid receptor, thereby influencing pain processing in the central nervous system. Due to its high potential for addiction and risks for respiratory depression, careful handling is required. The substance is medically used for the treatment of moderate to severe pain.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
Designations
IUPAC: (4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Substance Fingerprint
Pharmacological profile based on receptor binding, mechanism of action, and substance class. Limited data — interpret profile with caution.
Effects & Pharmacology is partially translated. Some content may appear in German.
Oxycodone primarily acts as an agonist at the μ-opioid receptor, leading to inhibition of pain transmission in the central nervous system. This results in analgesic effects as well as potential sedation.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Total duration 4-6 hours
Peak
1-2 hours
Onset
30-60 minutes
Total duration
4-6 hours
After effects
2-4 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Evidence
strong
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Some combinations can be dangerous. Research before combining substances.
Lebensbedrohlich: Atemdepression und erhöhte Opioid-Plasmaspiegel
Oxycodon ist ein potenter μ-Opioid-Agonist. Ethanol verstärkt die ZNS-depressive Wirkung über GABAerge Mechanismen und kann bei retardierten Oxycodon-Formulierungen zu einer schnellen unkontrollierten Wirkstofffreisetzung führen (Dose-Dumping). Die resultierende akute Opioid-Intoxikation kann tödlich verlaufen.
Lebensbedrohlich: Additive Atemdepression
Oxycodon und Benzodiazepine hemmen den Atemantrieb über unterschiedliche, komplementäre Mechanismen. Die Kombination ist eine häufige Ursache für arzneimittelbezogene Todesfälle. Die FDA und die EMA empfehlen, diese Substanzkombination zu vermeiden.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.