Laden…
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Reserpine is a plant alkaloid that acts as an antihypertensive by inhibiting the storage of monoamines in synaptic vesicles. This leads to a depletion of neurotransmitters such as dopamine, norepinephrine, and serotonin. Due to its mechanism of action, reserpine can induce sedative effects and is used in the treatment of hypertension. Side effects may include depressive symptoms.
Class
Alkaloide
Pharmacological context
Mechanism
Reserpin wirkt, indem es die Speicherung von Monoaminen in den...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid methyl ester
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Reported range 0.5–1 mg
Total duration 24 hours
Oral
| Tier | Dosage |
|---|---|
| Light | 0.1 mg |
| Reported | 0.5–1 mg |
| Strong | 2–5 mg |
Oral
Onset
1–2 hours
Peak
4–6 hours
Total duration
24 hours
After effects
Up - 48 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Kann zu Sedierung, Hypotonie und Depression führen.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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