Methylphenidat — Safer Use

Safer-Use-Hinweise

Warnungen

• ⚠Pre-existing structural cardiac abnormalities are a contraindication — sudden cardiac death has been reported; cardiac evaluation before prescribing in at-risk patients
• ⚠MPH + MAOI: hypertensive crisis risk — MAOI washout period of at least 14 days required
• ⚠Abuse potential increases dramatically with non-oral routes — insufflation or injection produces amphetamine-like effects with high addiction liability
• ⚠Growth suppression in children with long-term use — treatment breaks and height/weight monitoring are recommended
• ⚠Psychosis can be induced or unmasked at high doses — screen for personal/family history of psychotic disorders before prescribing
• ⚠Take the lowest effective dose; work with a prescriber to find the minimum effective dose rather than escalating
• ⚠Avoid taking late in the day — insomnia is dose- and timing-dependent
• ⚠Do not crush extended-release formulations (Concerta) — releases full 12-hour dose immediately