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5-(2-chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-one
Clonazepam is a benzodiazepine that primarily acts by enhancing GABAergic inhibition in the central nervous system. It is mainly used for the treatment of epilepsy and panic disorders. The substance possesses anxiolytic, anticonvulsive, and muscle relaxant properties. Due to its potential for dependence, its use should be carefully monitored.
Receptor Targets
Mechanism of Action
Designations
IUPAC: Clonazepam
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Receptor Profile
Der GABA-A-Rezeptor ist ein ligandengesteuerter Chloridkanal und der wichtigste inhibitorische Rezeptor im zentralen Nervensystem. Er besitzt multiple allosterische Bindungsstellen für verschiedene Substanzklassen.
Clonazepam acts as an agonist at the GABA-A receptor, leading to increased inhibition of neuronal activity. This results in anxiolytic, sedative, and muscle relaxant effects.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Total duration 6-12 hours
Peak
1-2 hours
Onset
30-60 minutes
Total duration
6-12 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, and pre-existing conditions significantly affect outcomes.
Risks
Summary
Mögliche Abhängigkeit und Toleranzentwicklung bei längerem Gebrauch.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Alcohol
Opioids
Other benzodiazepines
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.